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Gene Expression Literature Summary
Assay
Age
In situ reporter (knock in)
9.5 DPC

8 matching records from 8 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Nkx2-5  NK2 homeobox 5   (Synonyms: Csx, Nkx-2.5, Nkx2.5, tinman)
Results  Reference
1J:199431 Macdonald ST, Bamforth SD, Braganca J, Chen CM, Broadbent C, Schneider JE, Schwartz RJ, Bhattacharya S, A cell-autonomous role of Cited2 in controlling myocardial and coronary vascular development. Eur Heart J. 2013 Aug;34(32):2557-2565
1J:344070 Olejnickova V, Hamor PU, Janacek J, Bartos M, Zabrodska E, Sankova B, Kvasilova A, Kolesova H, Sedmera D, Development of ventricular trabeculae affects electrical conduction in the early endothermic heart. Dev Dyn. 2024 Jan;253(1):78-90
1J:313297 Olejnickova V, Sankova B, Sedmera D, Janacek J, Trabecular Architecture Determines Impulse Propagation Through the Early Embryonic Mouse Heart. Front Physiol. 2018;9:1876
1J:185712 Prall OW, Menon MK, Solloway MJ, Watanabe Y, Zaffran S, Bajolle F, Biben C, McBride JJ, Robertson BR, Chaulet H, Stennard FA, Wise N, Schaft D, Wolstein O, Furtado MB, Shiratori H, Chien KR, Hamada H, Black BL, Saga Y, Robertson EJ, Buckingham ME, HarveyRP, An Nkx2-5/Bmp2/Smad1 negative feedback loop controls heart progenitor specification and proliferation. Cell. 2007 Mar 9;128(5):947-59
1J:98489 Stennard FA, Costa MW, Lai D, Biben C, Furtado MB, Solloway MJ, McCulley DJ, Leimena C, Preis JI, Dunwoodie SL, Elliott DE, Prall OW, Black BL, Fatkin D, Harvey RP, Murine T-box transcription factor Tbx20 acts as a repressor during heart development, and is essential for adult heart integrity, function and adaptation. Development. 2005 May;132(10):2451-62
1J:227907 Sultana N, Zhang L, Yan J, Chen J, Cai W, Razzaque S, Jeong D, Sheng W, Bu L, Xu M, Huang GY, Hajjar RJ, Zhou B, Moon A, Cai CL, Resident c-kit(+) cells in the heart are not cardiac stem cells. Nat Commun. 2015;6:8701
1*J:52597 Tanaka M, Chen Z, Bartunkova S, Yamasaki N, Izumo S, The cardiac homeobox gene Csx/Nkx2.5 lies genetically upstream of multiple genes essential for heart development. Development. 1999 Mar;126(6):1269-80
1*J:205034 Zhou B, Pu WT, Genetic Cre-loxP assessment of epicardial cell fate using Wt1-driven Cre alleles. Circ Res. 2012 Nov 9;111(11):e276-80

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory